The present study examined which of the two main CLA isomers, trans-10, cis-12 CLA ( t10 c12) or cis-9, trans-11 CLA ( c9 t11), decreases colon tumor numbers and the mechanisms for this effect. ![]() We have previously shown that a diet containing a mixture of conjugated linoleic acid (CLA) isomers reduces the incidence of colon tumors in rats treated with 1,2-dimethylhydrazine (DMH).
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